Anti-RANBP9 monoclonal antibody, clone FQS0031(C)

Antibody Isotype

IgG

Clone

FQS0031(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)

Conjugate

Application Notes

WB: 1/1000 - 1/10000; ICC/IF: 1/100 - 1/250.

Alternative Names

RANBP9; RAN binding protein 9; ran-binding protein 9; Ran Binding Protein in the Microtubule organizing center; RanBPM; ran-binding protein M; novel centrosomal protein RanBPM; ran binding protein, centrosomal; BPM-L; BPM90; RANBPM; RanBP7;

Entrez Gene ID

UniProt ID

Antigen Description

May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.

Pathway

Androgen Receptor Signaling Pathway, organism-specific biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; L1CAM interactions, organism-specific biosystem; Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met), organism-specific biosystem;