Synthetic peptide corresponding to a region within the internal amino acids 252-301 (KDKPRYLMGV GYATDLVVCV ALGCDMFDCV FPTRTARFGS ALVPTGNLQL) of Human QTRT1 (NP_112486).
Interacts with QTRTD1 to form an active queuine tRNA-ribosyltransferase. This enzyme exchanges queuine for the guanine at the wobble position of tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), thereby forming the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).
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