Anti-Pneumolysin monoclonal antibody (DMAB5766)

Mouse anti-Streptococcus pneumoniae Pneumolysin monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
IZC 042-02
Species Reactivity
Streptococcus pneumoniae
Immunogen
Pneumolysin.
Conjugate
Unconjugated

Target


Alternative Names
Pneumolysin

Product Background


Antigen Description
Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes and is therefore cytotoxic to mammalian cell. The molecular weight of pneumolysin is approximately 53 kD.

Citations


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References


Vallina-Garcia, R; Garcia-Suarez, MD; et al. Oriented immobilisation of anti-pneumolysin Fab through a histidine tag for electrochemical immunosensors. BIOSENSORS & BIOELECTRONICS 23:210-217(2007).
Michelow, IC; Olsen, K; et al. Epidemiology and clinical characteristics of community-acquired pneumonia in hospitalized children. PEDIATRICS 113:701-707(2004).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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