Anti-Pneumolysin monoclonal antibody (DMAB5766)

Mouse anti-Streptococcus pneumoniae Pneumolysin monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
IZC 042-02
Species Reactivity
Streptococcus pneumoniae
Immunogen
Pneumolysin.
Conjugate
Unconjugated

Target


Alternative Names
Pneumolysin

Product Background


Antigen Description
Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes and is therefore cytotoxic to mammalian cell. The molecular weight of pneumolysin is approximately 53 kD.

Citations


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References


VIROLAINEN, A; JERO, J; et al. NASOPHARYNGEAL ANTIBODIES TO PNEUMOCOCCAL PNEUMOLYSIN IN CHILDREN WITH ACUTE OTITIS-MEDIA. CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY 2:704-707(1995).
Parker, D; Martin, FJ; et al. Streptococcus pneumoniae DNA Initiates Type I Interferon Signaling in the Respiratory Tract. MBIO 2:-(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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