Anti-Pneumolysin monoclonal antibody (DMAB5766)

Mouse anti-Streptococcus pneumoniae Pneumolysin monoclonal antibody for ELISA, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
IZC 042-02
Species Reactivity
Streptococcus pneumoniae
Immunogen
Pneumolysin.
Conjugate
Unconjugated

Target


Alternative Names
Pneumolysin

Product Background


Antigen Description
Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes and is therefore cytotoxic to mammalian cell. The molecular weight of pneumolysin is approximately 53 kD.

Citations


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References


Garcia-Suarez, MD; Florez, N; et al. The role of pneumolysin in mediating lung damage in a lethal pneumococcal pneumonia murine model. RESPIRATORY RESEARCH 8:-(2007).
FORGIE, IM; ONEILL, KP; et al. ETIOLOGY OF ACUTE LOWER RESPIRATORY-TRACT INFECTIONS IN GAMBIAN CHILDREN .1. ACUTE LOWER RESPIRATORY-TRACT INFECTIONS IN INFANTS PRESENTING AT THE HOSPITAL. PEDIATRIC INFECTIOUS DISEASE JOURNAL 10:33-41(1991).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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