Anti-Pneumolysin monoclonal antibody (DMAB5766)
Mouse anti-Streptococcus pneumoniae Pneumolysin monoclonal antibody for ELISA, WB
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Pneumolysin is a putative virulence factor of the gram-positive bacteria Streptococcus pneumoniae. Pneumolysin (pneumococcal hemolysin) is an intracellular protein produced by all strains of S. pneumoniae and is a cytoplasmic cholesterol-dependent cytolysin forming large pores in cholesterol-containing membranes and is therefore cytotoxic to mammalian cell. The molecular weight of pneumolysin is approximately 53 kD.
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Malley, R; Anderson, PW; et al. Serotype-independent pneumococcal experimental vaccines that induce cellular as well as humoral immunity. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:3623-3627(2012).
VIROLAINEN, A; JERO, J; et al. ANTIBODIES TO PNEUMOLYSIN AND PNEUMOCOCCAL CAPSULAR POLYSACCHARIDES IN MIDDLE-EAR FLUID OF CHILDREN WITH ACUTE OTITIS-MEDIA. ACTA OTO-LARYNGOLOGICA 115:796-803(1995).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.