General Notes
This product (Catalog No. DPABH-21017) is a rabbit-derived polyclonal antibody raised against human PZP, targeting the amino acid region 341–690 of the protein. It has been affinity purified by Protein A. Pregnancy zone protein (PZP) is a high-molecular-weight glycoprotein belonging to the α2-macroglobulin superfamily of protease inhibitors and extracellular chaperones. It is encoded by the PZP gene located on chromosome 12p13.31 and consists of a 720-kDa tetrameric structure formed by two covalently bound 180-kDa subunits, exhibiting approximately 71% sequence homology with α2-macroglobulin. In non-pregnant individuals, PZP circulates at low levels (10–40 mg/L in women and less than 10 mg/L in men), but its concentration surges dramatically during pregnancy—up to 1–3 g/L by late gestation—due to estrogen-dependent regulation, before rapidly declining postpartum.
DPABH-21017 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-21017 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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