Housekeeping enzyme that catalyzes the last step in proline biosynthesis. In some cell types, such as erythrocytes, its primary function may be the generation of NADP(+). Can utilize both NAD and NADP. Has higher affinity for NADP, but higher catalytic efficiency with NADH.
Pathway
Arginine and proline metabolism; Metabolic pathways; Proline biosynthesis, glutamate =>proline;
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