Full length protein corresponding to Human PWP2H aa 1-919.Sequence: MKFAYRFSNLLGTVYRRGNLNFTCDGNSVISPVGNRVTVFDLKNNKSDTL PLATRYNVKCVGLSPDGRLAIIVDEGGDALLVSLVCRSVLHHFHFKGSVH SVSFSPDGRKFVVTKGNIAQMYHAPGKKREFNAFVLDKTYFGPYDETTCI DWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYAL
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
PWP2; PWP2 periodic tryptophan protein homolog (yeast); UTP1; PWP2H; EHOC-17; periodic tryptophan protein 2 homolog;
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Pathway
Ribosome biogenesis in eukaryotes;
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Spellman, C; Ahmed, MM; et al. Expression of trisomic proteins in Down syndrome model systems. GENE 512:219-225(2013).
Parente, JA; Salem-Izacc, SM; et al. A secreted serine protease of Paracoccidioides brasiliensis and its interactions with fungal proteins. BMC MICROBIOLOGY 10:-(2010).
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COA
Certificate of Analysis