Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PCPTP1 aa 1-100. The exact sequence is proprietary.Database link: Q15256
Sequesters mitogen-activated protein kinases (MAPKs) such as MAPK1, MAPK3 and MAPK14 in the cytoplasm in an inactive form. The MAPKs bind to a dephosphorylated kinase interacting motif, phosphorylation of which by the protein kinase A complex releases the MAPKs for activation and translocation into the nucleus.
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