General Notes
This product (Catalog No. DPABH-21677) is a rabbit-derived polyclonal antibody raised against human PTPN14, targeting the amino acid region 1–351 of the protein. It has been affinity purified by Protein A. PTPN14 (tyrosine-protein phosphatase non-receptor type 14) is also named as PEZ and belongs to the protein-tyrosine phosphatase family and non-receptor class subfamily. It is a multi-domain protein expressed in breast, kidney, skeletal muscle, lung, placenta, and characterized by an N-terminal FERM domain and a C-terminal PTP domain with an intervening sequence containing an acidic region and a putative SH3 domain-binding sequence (PMID: 21701840). Defects in PTPN14 are a cause of choanal atresia and lymphedema (CHATLY).
DPABH-21677 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:20–1:200) applications.
DPABH-21677 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.