Anti-PTPMT1 polyclonal antibody (DPABH-07180)

Mouse Anti-Human PTPMT1 (full length) polyclonal antibody for WB

Specifications


Host Species
Mouse
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant full length Human PTPMT1 (amino acids 1-201; AAH20242.1).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PTPMT1; protein tyrosine phosphatase, mitochondrial 1; protein-tyrosine phosphatase mitochondrial 1; DUSP23; MOSP; PLIP
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Protein phosphatase that specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. The function about PTPMT1 antigen include hydrolase activity; phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; protein tyrosine phosphatase activity; protein tyrosine/serine/threonine phosphatase activity.
Pathway
3-phosphoinositide degradation.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Quaio, CRDC; Carvalho, JF; et al. Autoimmune disease and multiple autoantibodies in 42 patients with RASopathies. AMERICAN JOURNAL OF MEDICAL GENETICS PART A 158A:1077-1082(2012).
Joucher, F; Mazmanian, GM; et al. Role of E-selectin in cell apoptosis induced by allogeneic blood perfusion in isolated mouse lung. TRANSPLANTATION 80:666-672(2005).

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