Synthetic peptide within Human PTP4A2 aa 38-68 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q12974
PTP4A2; protein tyrosine phosphatase type IVA, member 2; PTP4A; protein tyrosine phosphatase type IVA 2; HU PP 1; OV 1; PRL 2; ptp IV1a; PTPCAAX2; PTP(CAAXII); protein tyrosine phosphatase IVA; protein-tyrosine phosphatase 4a2; protein tyrosine phosphatas
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Promotes tumors. Inhibits geranylgeranyl transferase type II activity by blocking the association between RABGGTA and RABGGTB. Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
Pathway
Signaling events mediated by PRL;
Citations
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