Anti-PTGES monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PTGES is used for rabbit immunization.

Conjugate

Alternative Names

PTGES; prostaglandin E synthase; MGST1L1; glutathione S transferase 1 like 1; MGST IV; MGST1 L1; MGST1 like 1; microsomal glutathione S transferase 1 like 1; microsomal prostaglandin E synthase 1; p53 induced gene 12; PIG12; TP53I12; tumor protein p53 ind

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Pathway

Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem;