Anti-PTDSS1 monoclonal antibody, clone FQS9229(3)

Antibody Isotype

IgG

Clone

FQS9229(3)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide corresponding to a region within Human PTDSS1 (P48651).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IP: 1/10 - 1/100;

Alternative Names

PTDSS1; phosphatidylserine synthase 1; KIAA0024; PSS1; PSSA; PSS-1; ptdSer synthase 1; serine-exchange enzyme I;

Entrez Gene ID

UniProt ID

Antigen Description

Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a calcium dependent base exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS1, that exchange L-serine for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001 [PubMed 11084049]).

Pathway

Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem;