Anti-PSMC5 monoclonal antibody, clone FQS24677(C)

Antibody Isotype

IgG

Clone

FQS24677(C)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PSMC5 aa 350 to the C-terminus (C terminal). The exact sequence is proprietary.Database link: P62195

Conjugate

Application Notes

WB: 1/1000 - 1/10000; ICC/IF: 1/500; Flow Cyt: 1/30; IHC-P: 1/250.

Alternative Names

PSMC5; proteasome (prosome, macropain) 26S subunit, ATPase, 5; 26S protease regulatory subunit 8; p45; p45/SUG; S8; SUG 1; SUG1; TBP10; TRIP1; MSUG1 protein; proteasome subunit p45; thyroid receptor interactor 1; Tat-binding protein homolog 10; proteasome

Entrez Gene ID

UniProt ID

Antigen Description

The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.

Pathway

APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem;