Anti-PSEN2 polyclonal antibody (DPABH-23467)

Rabbit anti-Human PSEN2 (aa 319-334) polyclonal antibody for WB, IHC-P, IHC-Fr Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Human
Immunogen
Synthetic peptide: YDPEMEEDSYDSFGEP, corresponding to internal sequence amino acids 319-334 of Human Presenilin 2
Conjugate
Unconjugated

Applications


Application Notes
WB: 1μg/ml; IHC-P: 1μg/ml; IHC-Fr: 1μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PSEN2; presenilin 2; AD4; PS2; AD3L; STM2
Entrez Gene ID
UniProt ID

Product Background


Pathway
Activated NOTCH1 Transmits Signal to the Nucleus; Alzheimers disease; Cell death signalling via NRAGE, NRIF and NADE; Constitutive Signaling by NOTCH1 PEST Domain Mutants

Citations


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References


Nornes, S; Groth, C; et al. Developmental control of Presenilin1 expression, endoproteolysis, and interaction in zebrafish embryos. EXPERIMENTAL CELL RESEARCH 289:124-132(2003).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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