This product (Catalog No. DPABH-03433) is a rabbit-derived polyclonal antibody raised against human PROSC, targeting the amino acid region 1–275 of the protein. It has been affinity purified by Protein A. Human Pyridoxal 5′-phosphate-binding protein (PLPBP; previously proline synthase cotranscribed homolog, PROSC) was first described in 1999 and was demonstrated to be ubiquitously expressed in many tissues. PROSC is ubiquitously expressed in human tissues and is highly conserved throughout evolution. PROSC deficiency could therefore markedly increase free cellular PLP levels (PMID: 31825581, 27912044). DPABH-03433 is suitable for use in Western blot (WB) (1:1,000–1:6,000), IHC (1:100–1:400), IF/ICC (1:50–1:500) applications. DPABH-03433 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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