Anti-PRODH (aa 441-540) polyclonal antibody

Species Reactivity

Human

Immunogen

PRODH (NP_057419, 441 a.a. ~ 540 a.a) partial recombinant protein with GST tag. The sequence is LVRGAYLAQERARAAEIGYEDPINPTYEATNAMYHRCLDYVLEELKHNAKAKVMVASHNE DTVRFALRRMEELGLHPADHRVYFGQLLGMCDQISFPLGQ

Conjugate

Alternative Names

PRODH; proline dehydrogenase (oxidase) 1; POX; PIG6; HSPOX2; PRODH1; PRODH2; TP53I6; proline dehydrogenase 1, mitochondrial; proline oxidase 2; p53-induced gene 6 protein; proline oxidase, mitochondrial; tumor protein p53 inducible protein 6;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pathway

Arginine and proline metabolism; Metabolism; Proline catabolism; proline degradation