Rabbit Anti-Human PRMT7 (a.a. 353-693) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

Recombinant human PRMT7 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 353-693 aa of BC000146

Conjugate

Application Notes

WB: 1:1000-1:4000
IP: 0.5-4.0 μg for 1.0-3.0 mg of total protein lysate

General Notes

This product (Catalog No. DPABH-20717) is a rabbit-derived polyclonal antibody raised against human PRMT7, targeting the amino acid region 353–693 of the protein. This antibody exhibits cross-reactivity with Human PRMT7 from mouse. It has been affinity purified by Protein A. Protein arginine methyltransferases (PRMTs) are responsible for arginine methylation of histone or nonhistone proteins to regulate diverse biological processes, including cell proliferation, differentiation and senescence. PRMT7 is expressed in both embryonic stem and germ cells and is implicated in maintenance of muscle stem cell function. overexpression of PRMT7 has been associated with cancer metastasis. PRMT7 automethylation at residue R531 was reported to enhance breast cancer metastasis.
DPABH-20717 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate) applications.
DPABH-20717 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Protein arginine N-methyltransferase 7; PRMT 7; Histone-arginine N-methyltransferase PRMT7; EC:2.1.1.321; [Myelin basic protein]-arginine N-methyltransferase PRMT7

Entrez Gene ID

UniProt ID