Specifications
Immunogen
A synthetic peptide of human PRIM2 is used for rabbit immunization.
Target
Alternative Names
PRIM2; primase, DNA, polypeptide 2 (58kDa); PRIM2A, primase, polypeptide 2A (58kD) , primase, polypeptide 2A, 58kDa; DNA primase large subunit; dJ422B11.1.1; DNA primase subunit p58; DNA primase 58 kDa subunit; primase polypeptide 2A, 58kDa; p58; PRIM2A;
Product Background
Antigen Description
The replication of DNA in eukaryotic cells is carried out by a complex chromosomal replication apparatus, in which DNA polymerase alpha and primase are two key enzymatic components. Primase, which is a heterodimer of a small subunit and a large subunit, synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. The protein encoded by this gene is the large, 58 kDa primase subunit.
Pathway
Activation of the pre-replicative complex, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; DNA Replication, organism-specific biosystem; DNA Replication Pre-Initiation, organism-specific biosystem.
Citations
Publication ()
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