Rabbit Anti-Human PPP2R1B (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthesized peptide derived from internal of human PPP2R1B.

Conjugate

Application Notes

WB: 1:500-1:3000
IHC: 1:50-1:100

General Notes

This product (Catalog No. DPABH-28938) is a rabbit-derived IgG polyclonal antibody raised against human PPP2R1B. It has been affinity purified by protein A. This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
DPABH-28938 is suitable for use in Western blot (WB) (1:500–1:3,000), IHC (1:50–1:100) applications.
DPABH-28938 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

2AAB; beta isoform of regulatory subunit A; protein phosphatase 2; PP2A; A

Entrez Gene ID

UniProt ID