Recombinant fragment corresponding to Human PP1C gamma (N terminal).Sequence: DSIIQRLLEVRGSKPGKNVQLQENEIRGLCLKSREIFLSQPILLELEAPL KICGDIHGQYYDLLRLFEYGGFPPESNYLFLGDYVDDatabase link: BC014073
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/1000;
Target
Alternative Names
PPP1CC; protein phosphatase 1, catalytic subunit, gamma isozyme; PP1C; PP-1G; PPP1G; serine/threonine-protein phosphatase PP1-gamma catalytic subunit; serine/threonine phosphatase 1 gamma; protein phosphatase 1C catalytic subunit; protein phosphatase 1, c
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
Pathway
Adrenergic signaling in cardiomyocytes; Alcoholism; Amphetamine addiction; Aurora B signaling
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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OMAY, SB; NISHIKAWA, M; et al. DECREASED EXPRESSION OF PROTEIN PHOSPHATASE TYPE 2A IN HL-60 VARIANT (HL-6ORA) CELLS RESISTANT TO INDUCTION OF CELL-DIFFERENTIATION BY ALL-TRANS-RETINOIC ACID. EXPERIMENTAL HEMATOLOGY 23:244-251(1995).
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