Anti-PPM1A monoclonal antibody (DCABH-3209) Knockout Validated

Mouse anti-Human PPM1A monoclonal antibody for WB, ELISA, FC

Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
8G23
Species Reactivity
Human, Monkey
Immunogen
Purified recombinant fragment corresponding to amino acids 202-382 of Human PPM1A, expressed in E. coli.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; ELISA: 1/10000; Flow Cyt: 1/200 - 1/400;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PPM1A; protein phosphatase, Mg2+/Mn2+ dependent, 1A; protein phosphatase 1A (formerly 2C), magnesium dependent, alpha isoform; protein phosphatase 1A; MGC9201; phosphatase 2C alpha
Entrez Gene ID
UniProt ID

Product Background


Pathway
BMP receptor signaling, organism-specific biosystem; Energy dependent regulation of mTOR by LKB1-AMPK, organism-specific biosystem; IRS-mediated signalling, organism-specific biosystem; IRS-related events, organism-specific biosystem; Insulin receptor signalling cascade, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem; MAPK signaling pathway, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Kim, YG; Sohn, DH; et al. Role of Protein Phosphatase Magnesium-Dependent 1A and Anti-Protein Phosphatase Magnesium-Dependent 1A Autoantibodies in Ankylosing Spondylitis. ARTHRITIS & RHEUMATOLOGY 66:2793-2803(2014).
Voss, M; Paterson, J; et al. Ppm1E is an in cellulo AMP-activated protein kinase phosphatase. CELLULAR SIGNALLING 23:114-124(2011).

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