Anti-PPAP2C monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PPAP2C is used for rabbit immunization.

Conjugate

Alternative Names

PPAP2C; phosphatidic acid phosphatase type 2C; lipid phosphate phosphohydrolase 2; LPP2; PAP 2c; PAP2c; PAP2-gamma; phosphatidic acid phosphatase 2c; phosphatidate phosphohydrolase type 2c; phosphatidic acid phosphohydrolase type 2c; type-2 phosphatidic a

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is similar to phosphatidic acid phosphatase type 2A (PPAP2A) and type 2B (PPAP2B). All three proteins contain 6 transmembrane regions, and a consensus N-glycosylation site. This protein has been shown to possess membrane associated PAP activity. Three alternatively spliced transcript variants encoding distinct isoforms have been reported.

Pathway

Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Fat digestion and absorption, organism-specific biosystem; Fat digestion and absorption, conserved biosystem; Fc gamma R-mediated phagocytosis, organism-specific biosystem; Fc gamma R-mediated phagocytosis, conserved biosystem; Glycerolipid metabolism, organism-specific biosystem.