Anti-POLR2J2 monoclonal antibody, clone 4H5

Antibody Isotype

IgG2a

Clone

4H5

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human POLR2J2 (NP_116581) produced in HEK293T cells.

Conjugate

Application Notes

WB: 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;

Alternative Names

POLR2J2; polymerase (RNA) II (DNA directed) polypeptide J2; DNA-directed RNA polymerase II subunit RPB11-b1; RPB11b1; RNA polymerase II subunit B11-b1; DNA-directed RNA polymerase II subunit J2; DNA directed RNA polymerase II polypeptide J-related; HRPB11

Entrez Gene ID

UniProt ID

Antigen Description

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB11 is part of the core element with the central large cleft.

Pathway

Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem; Metabolic pathways, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem;