POLR1B (NP_061887, 963 a.a. ~ 1072 a.a) partial recombinant protein with GST tag. The sequence is GEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVT NQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVK
Conjugate
Unconjugated
Target
Alternative Names
POLR1B; polymerase (RNA) I polypeptide B, 128kDa; RPA2; RPA135; Rpo1-2; DNA-directed RNA polymerase I subunit RPA2; RNA polymerase I subunit 2; DNA-directed RNA polymerase I 135kDa polypeptide; DNA-directed RNA polymerase I 135 kDa polypeptide;
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM, Mar 2008]
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