POLD3 (NP_006582, 357 a.a. ~ 466 a.a) partial recombinant protein with GST tag. The sequence is PPLEPVPKTEPEPPSVKSSSGENKRKRKRVLKSKTYLDGEGCIVTEKVYESESCTDSEEE LNMKTSSVHRPPAMTVKKEPREERKGPKKGTAALGKANRQVSITGFFQRK
Conjugate
Unconjugated
Target
Alternative Names
POLD3; polymerase (DNA-directed), delta 3, accessory subunit; P66; P68; PPP1R128; DNA polymerase delta subunit 3; Pol delta C subunit (p66); DNA polymerase delta subunit p66; protein phosphatase 1, regulatory subunit 128;
This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3 to 5 exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene.
Pathway
Base Excision Repair; Base excision repair; Cell Cycle, Mitotic; DNA Repair
Citations
Publication ()
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COA
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