General Notes
This product (Catalog No. DPABH-16505) is a rabbit-derived polyclonal antibody raised against human PNPLA7, targeting the amino acid region 302–468 of the protein. This antibody exhibits cross-reactivity with Human PNPLA7 from mouse. It has been affinity purified by Protein A. PNPLA7 (Patatin-like phospholipase domain-containing protein 7), also termed NTE-related 1 (NTE-R1) or NRE, is a member of the PNPLAs family, which is conserved protein in mice, rats and humans. It serves key roles in triglyceride hydrolysis, energy metabolism, lipid droplet (LD), and in regulation of adipocyte differentiation. It is reported that PNPLA7 was down-regulated in HCC through hypermethylation of its promoter, which indicates that PNPLA7 may be a potential biomarker for HCC diagnosis (PMID: 16799181, 27347198).
DPABH-16505 is suitable for use in IHC (1:50–1:500) application.
DPABH-16505 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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