Anti-PNPLA6 polyclonal antibody

Species Reactivity

Human

Immunogen

A synthetic peptide corresponding to amino acids at internal region of human PNPLA6. The sequence is C-YQGRQTSSIFEAAKQ

Conjugate

Unconjugated

Application Notes

ELISA: 1:2000. & The optimal working dilution should be determined by the end user.

Alternative Names

PNPLA6; patatin-like phospholipase domain containing 6; NTE; sws; BNHS; SPG39; NTEMND; iPLA2delta; neuropathy target esterase; patatin-like phospholipase domain-containing protein 6;

Entrez Gene ID

10908

UniProt ID

Q8IY17

Antigen Description

This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Glycerophospholipid metabolism.

We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More