Anti-PLEKHG6 polyclonal antibody (DPABH-02166)

Rabbit anti-Human PLEKHG6 (aa 196-453) polyclonal antibody for WB, IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to amino acids 196-453 of Human MyoGEF
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/2000; IHC-P: 1/100 - 1/500;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PLEKHG6; pleckstrin homology domain containing, family G (with RhoGef domain) member 6; MyoGEF; pleckstrin homology domain-containing family G member 6; PH domain-containing family G member 6; myosin interacting guanine nucleotide exchange factor
Entrez Gene ID
UniProt ID

Product Background


Pathway
Regulation of RhoA activity;

Citations


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References


Zhang, P; Ma, YL; et al. Comprehensive gene and microRNA expression profiling reveals the crucial role of hsa-let-7i and its target genes in colorectal cancer metastasis. MOLECULAR BIOLOGY REPORTS 39:1471-1478(2012).
D'Angelo, R; Aresta, S; et al. Interaction of ezrin with the novel guanine nucleotide exchange factor PLEKHG6 promotes RhoG-dependent apical cytoskeleton rearrangements in epithelial cells. MOLECULAR BIOLOGY OF THE CELL 18:4780-4793(2007).

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