A synthetic peptide of human PLEKHG2 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
PLEKHG2; pleckstrin homology domain containing, family G (with RhoGef domain) member 2; pleckstrin homology domain-containing family G member 2; ARHGEF42; CLG; FLJ00018; PH domain-containing family G member 2; common-site lymphoma/leukemia guanine nucleot
May be a transforming oncogene with exchange activity for CDC42 (By similarity). May be a guanine-nucleotide exchange factor (GEF) for RAC1 and CDC42. Activated by the binding to subunits beta and gamma of the heterotrimeric guanine nucleotide-binding protein (G protein).
Pathway
Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; G alpha (12/13) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; NRAGE signals death through JNK, organism-specific biosyst.
Citations
Publication ()
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COA
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