Anti-PLEKHG1 polyclonal antibody (DPABH-20261)

Rabbit anti-Human PLEKHG1 (aa 1158-1252) polyclonal antibody for ICC/IF,IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
antigen sequence: CQDHLYNSLG RKGISAKSQP YHRSQSSSSV LINKSMDSIN YPSDVGKQQL LSLHRSSRCE SHQDLLPDIA DSHQQGTEKL SDLTLQDSQK VVVVN, corresponding to internal sequence amino acids 1158-1252 of Human PKHG1.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1 - 4 μg/ml. IHC-P: 1/50 - 1/200.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PLEKHG1; pleckstrin homology domain containing, family G (with RhoGef domain) member 1; ARHGEF41; pleckstrin homology domain-containing family G member 1
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
PLEKHG1 (pleckstrin homology domain containing, family G (with RhoGef domain) member 1) is a protein-coding gene. Diseases associated with PLEKHG1 include panic disorder , and alcoholism. GO annotations related to this gene include phospholipid binding and Rho guanyl-nucleotide exchange factor activity. An important paralog of this gene is ARHGEF6. The function about PLEKHG1 antigen include Rho guanyl-nucleotide exchange factor activity.

Citations


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References


Zinovyeva, M; Sveshnikova, E; et al. Molecular cloning, sequence and expression pattern analysis of the mouse orthologue of the leukemia-associated guanine nucleotide exchange factor. GENE 337:181-188(2004).
Tellermann, A; Witte, T; et al. Autoantibodies binding to ubiquitin-fold modifier-conjugating enzyme 1 (Ufc1) and pleckstrin homology domain containing, family G (with RhoGef domain) member 2 (Plekhg2) are associated with mycobacterial infections. HIV MEDICINE 16:114-121(2015).

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