Anti-PLB1 monoclonal antibody, clone 2C4

Antibody Isotype

IgG1

Clone

2C4

Species Reactivity

Human

Immunogen

Recombinant full length protein corresponding to Human PLB1. Produced in HEK293T cells (NP_694566).Database link: Q6P1J6

Conjugate

Application Notes

WB: 1/4000;

Alternative Names

PLB1; phospholipase B1; phospholipase B1, membrane-associated; FLJ30866; PLB; phospholipase B; phospholipase A2; lysophospholipase; phospholipase B/lipase; hPLB; PLB/LIP;

Entrez Gene ID

UniProt ID

Antigen Description

PLB1 is a membrane-associated phospholipase which exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. It shows preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. It also exhibits esterase activity toward p-nitrophenyl. It may act on the brush border membrane to facilitate the absorption of digested lipids.

Pathway

Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Ether lipid metabolism, organism-specific biosystem; Ether lipid metabolism, conserved biosystem; Glycerophospholipid metabolism, organism-specific biosystem; Glycerophospholipid metabolism, conserved biosystem; Linoleic acid metabolism, organism-specific biosystem.