Anti-PKNOX1 (aa 201-436) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment corresponding to a region within amino acids 201-436 of Human PKNOX1.1 (Uniprot ID P55347).

Conjugate

Application Notes

WB: 1/500 - 1/3000;

Alternative Names

PKNOX1; PBX/knotted 1 homeobox 1; PREP1; pkonx1c; homeobox protein PKNOX1; PBX/knotted homeobox 1; homeobox protein PREP-1; Pbx regulating protein-1; human homeobox-containing protein;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may be involved in molecular recruitment and stabilization during desmosome formation. Mutations in this gene have been associated with the ectodermal dysplasia/skin fragility syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Pathway

SIDS Susceptibility Pathways;