General Notes
This product (Catalog No. DPABH-05186) is a rabbit-derived polyclonal antibody raised against human PIR, targeting the amino acid region 1–290 of the protein. It has been affinity purified by Protein A. Probable quercetin 2,3-dioxygenase (Pirin, or PIR) is a highly conserved iron-binding protein within the cupin superfamily that acts as a flavonol 2,4-oxygenase, catalyzing the degradation of quercetin into 2-protocatechuoyl-phloroglucinol carboxylic acid and carbon monoxide. It plays roles in transcriptional regulation and is characterized by a two-domain beta-barrel structure, with activity in both bacteria and humans.
DPABH-05186 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-05186 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.