Anti-PIK3CD (aa 138-247) polyclonal antibody

Species Reactivity

Human

Immunogen

PIK3CD (NP_005017, 138 a.a. ~ 247 a.a) partial recombinant protein with GST tag. The sequence is DFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSAQTWGPGTLRLPNRALLVNVKFE GSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYTLQVNGRH

Conjugate

Alternative Names

PIK3CD; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta; APDS; PI3K; IMD14; p110D; P110DELTA; phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform; PI3Kdelta; phosphoinositide-3-kinase C; PI3-kinase p110 s

Entrez Gene ID

UniProt ID

Antigen Description

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by this gene is a class I PI3K found primarily in leukocytes. Like other class I PI3Ks (p110-alpha p110-beta, and p110-gamma), the encoded protein binds p85 adapter proteins and GTP-bound RAS. However, unlike the other class I PI3Ks, this protein phosphorylates itself, not p85 protein.[provided by RefSeq, Jul 2010]

Pathway

3-phosphoinositide biosynthesis; AMPK signaling pathway; Adaptive Immune System; Aldosterone-regulated sodium reabsorption.