Anti-PIGW monoclonal antibody, clone 2E9

Antibody Isotype

IgG2a

Clone

2E9

Species Reactivity

Human

Immunogen

PIGW (NP_848612.2, 399 a.a. ~ 447 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

PIGW; phosphatidylinositol glycan anchor biosynthesis, class W; phosphatidylinositol glycan, class W; phosphatidylinositol-glycan biosynthesis class W protein; FLJ37433; Gwt1; PIG-W;

Entrez Gene ID

UniProt ID

Antigen Description

Glycosylphosphatidylinositol (GPI) is a complex glycolipid that anchors many proteins to the cell surface. PIGW acts in the third step of GPI biosynthesis and acylates the inositol ring of phosphatidylinositol (Murakami et al., 2003 [PubMed 14517336]).

Pathway

GPI-anchor biosynthesis, core oligosaccharide, organism-specific biosystem; GPI-anchor biosynthesis, core oligosaccharide, conserved biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Post-translational modification: synthesis of GPI-anchored proteins, organism-specific biosyst