Anti-PIGN monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PIGN is used for rabbit immunization.

Conjugate

Alternative Names

PIGN; phosphatidylinositol glycan anchor biosynthesis, class N; phosphatidylinositol glycan, class N; GPI ethanolamine phosphate transferase 1; MDC4; PIG N; MCD4 homolog; phosphatidylinositol-glycan biosynthesis class N protein; MCD4; MCAHS; PIG-N; MCAHS1

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is expressed in the endoplasmic reticulum and transfers phosphoethanolamine (EtNP) to the first mannose of the GPI anchor. Two alternatively spliced variants, which encode an identical isoform, have been reported.

Pathway

GPI-anchor biosynthesis, core oligosaccharide, organism-specific biosystem; GPI-anchor biosynthesis, core oligosaccharide, conserved biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, organism-specific biosystem; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Post-translational modification: synthesis of GPI-anchored proteins, organism-specific biosyst.