PIGL (NP_004269, 153 a.a. ~ 252 a.a) partial recombinant protein with GST tag. The sequence is GHSNHIALYAAVRALHSEGKLPKGCSVLTLQSVNVLRKYISLLDLPLSLLHTQDVLFVLN SKEVAQAKKAMSCHRSQLLWFRRLYIIFSRYMRINSLSFL
Conjugate
Unconjugated
Target
Alternative Names
PIGL; phosphatidylinositol glycan anchor biosynthesis, class L; CHIME; N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase; PIG-L; phosphatidylinositol glycan, class L; N-acetylglucosaminylphosphatidylinositol deacetylase; phosphatidylinositol-glycan
This gene encodes an enzyme that catalyzes the second step of glycosylphosphatidylinositol (GPI) biosynthesis, which is the de-N-acetylation of N-acetylglucosaminylphosphatidylinositol (GlcNAc-PI). Study of a similar rat enzyme suggests that this protein localizes to the endoplasmic reticulum.
Pathway
GPI-anchor biosynthesis, core oligosaccharide; Glycosylphosphatidylinositol(GPI)-anchor biosynthesis; Metabolism of proteins; Post-translational protein modification
Citations
Publication ()
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