Specifications
Immunogen
Full length protein corresponding to Human PHKA2.Sequence: MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHEQKDAWVRDNIYS ILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVAKVE KFKHTQSTKDSLHAKYNTATCGTVVGDDQWGHLQVDATSLFLLFLAQMTA SGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQG
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
PHKA2; phosphorylase kinase, alpha 2 (liver); PHK, PYK; phosphorylase b kinase regulatory subunit alpha, liver isoform; phosphorylase kinase alpha-subunit; phosphorylase kinase alpha L subunit; phosphorylase b kinase regulatory subunit alpha liver isoform
Product Background
Antigen Description
PHKA2 belongs to the phosphorylase b kinase regulatory chain family. It is a polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin. It catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
Pathway
Calcium signaling pathway; Glucose metabolism; Glycogen Metabolism; Glycogen breakdown (glycogenolysis); Insulin signaling pathway;
Citations
Publication ()
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COA
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