Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human REA aa 150-250. The exact sequence is proprietary.Database link: Q99623
Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Ande, SR; Gu, YY; et al. Insulin induced phosphorylation of prohibitin at tyrosine114 recruits Shp1. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1793:1372-1378(2009).
Zhang, Y; Wang, Y; et al. Prohibitins are involved in protease-activated receptor 1-mediated platelet aggregation. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 10:411-418(2012).
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COA
Certificate of Analysis