Anti-PECR monoclonal antibody (DCABH-551)

Mouse anti-Human PECR monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
2F23
Species Reactivity
Human
Immunogen
Recombinant full length Human PECR produced in HEK293T cells (NP_060911).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
PECR; peroxisomal trans-2-enoyl-CoA reductase; HSA250303; SDR29C1; short chain dehydrogenase/reductase family 29C; member 1
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity. Peroxisomal trans-2-enoyl-CoA reductase is an enzyme that in humans is encoded by the PECR gene. 0The function about PECR antigen include nucleotide binding; oxidoreductase activity; trans-2-enoyl-CoA reductase (NADPH) activity.
Pathway
Biosynthesis of unsaturated fatty acids, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, conserved biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Mitochondrial LC-Fatty Acid Beta-Oxidation, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem.

Citations


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References


Freitas, M; Rebellato, L; et al. Antibody-Mediated Rejection (AMR) in Kidney Transplantation: The Role of Anti-Peroxisomal trans-2-enoyl-CoA Reductase (PECR) Auto-Antibody.. AMERICAN JOURNAL OF TRANSPLANTATION 13:333-333(2013).

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