Anti-PDSS1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PDSS1 is used for rabbit immunization.

Conjugate

Alternative Names

PDSS1; prenyl (decaprenyl) diphosphate synthase, subunit 1; TPRT, trans prenyltransferase; decaprenyl-diphosphate synthase subunit 1; coenzyme Q1 homolog (yeast); COQ1; TPT; coenzyme Q1 homolog; trans-prenyltransferase 1; trans-prenyltransferase (TPT); po

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is an enzyme that elongates the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. The protein may be peripherally associated with the inner mitochondrial membrane, though no transit peptide has been definitively identified to date. Defects in this gene are a cause of coenzyme Q10 deficiency.

Pathway

Terpenoid backbone biosynthesis, organism-specific biosystem; Terpenoid backbone biosynthesis, conserved biosystem; all-trans-decaprenyl diphosphate biosynthesis, organism-specific biosystem; all-trans-decaprenyl diphosphate biosynthesis, conserved biosystem;