Anti-PDLIM7 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length protein, corresponding to amino acids 1-457 of Human PDLIM7, Isoform 1 (NP_005442.2, Q9NR12-1).

Conjugate

Application Notes

WB: 1 μg/ml; ICC/IF: 10 μg/ml.

Alternative Names

PDLIM7; PDZ and LIM domain 7 (enigma); PDZ and LIM domain protein 7; ENIGMA; LMP; 1110003B01Rik; protein enigma; LIM domain protein; Lim mineralization protein 3; LMP1; LMP3;

Entrez Gene ID

UniProt ID

Antigen Description

May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway.

Pathway

Signaling events regulated by Ret tyrosine kinase;