General Notes
This product (Catalog No. DPABH-19700) is a rabbit-derived polyclonal antibody raised against human PDIA5. This antibody exhibits cross-reactivity with PDIA5 from mouse and rat. It has been affinity purified by Protein A. This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, three catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. The N-terminal TRX-like domain is the primary binding site for the major ER chaperone calreticulin and possibly other proteins and substrates as well. Alternative splicing results in multiple protein- and non-protein-coding transcript variants.
DPABH-19700 is suitable for use in Western blot (WB) (1:1,000–1:5,000), IHC (1:30–1:150) applications.
DPABH-19700 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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