Required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex.
Pathway
Glycolysis and Gluconeogenesis; Metabolic pathways; Metabolism; Pyruvate metabolism; Pyruvate metabolism and Citric Acid (TCA) cycle; Pyruvate oxidation, pyruvate =>acetyl-CoA
Citations
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