General Notes
This product (Catalog No. DPABH-10321) is a rabbit-derived IgG polyclonal antibody raised against human PDE6D, targeting the amino acid region 1–100 of the protein. This antibody exhibits cross-reactivity with PDE6D from rat, mouse, chicken, cow, horse, rabbit, and zebrafish. It has been affinity purified by Protein A. This gene encodes the delta subunit of rod-specific photoreceptor phosphodiesterase (PDE), a key enzyme in the phototransduction cascade. A similar protein in cow functions in solubilizing membrane-bound PDE. In addition to its role in the PDE complex, the encoded protein is thought to bind to prenyl groups of proteins to target them to subcellular organelles called cilia. Mutations in this gene are associated with Joubert syndrome-22. Alternative splicing results in multiple splice variants.
DPABH-10321 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500), ICC/IF (1:100–1:500), ELISA (1:5,000–1:10,000) applications.
DPABH-10321 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
PDE6 delta; 5''-cyclic phosphodiesterase subunit delta; GMP PDE delta; GMP-PDE delta; p17 protein; PDE 6; PDE 6D; PDE D; PDE6; PDE6D; PDE6D_HUMAN; PDED; Phosphodiesterase 6D cGMP specific; Phosphodiesterase 6D cGMP specific rod delta; Protein p17; Retinal rod photoreceptor cGMP phosphodiesterase delta; Retinal rod rhodopsin sensitive cGMP 3' 5' cyclic phosphodiesterase subunit delta; Retinal rod rhodopsin-sensitive cGMP 3''
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