Anti-PDE4C (aa 1-99) polyclonal antibody

Species Reactivity

Human

Immunogen

PDE4C (NP_000914, 1 a.a. ~ 99 a.a) partial recombinant protein with GST tag. The sequence is MENLGVGEGAEACSRLSRSRGRHSMTRAPKHLWRQPRRPIRIQQRFYSDPDKSAGCRERD LSPRPELRKSRLSWPVSSCRRFDLENGLSCGRRALDPQS

Conjugate

Alternative Names

PDE4C; phosphodiesterase 4C, cAMP-specific; DPDE1; cAMP-specific 3,5-cyclic phosphodiesterase 4C; PDE21; phosphodiesterase E1 dunce homolog; phosphodiesterase 4C, cAMP-specific (phosphodiesterase E1 dunce homolog, Drosophila);

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]

Pathway

DARPP-32 events; G alpha (s) signalling events; Morphine addiction; Opioid Signalling