Specifications
Immunogen
Recombinant fragment, corresponding to amino acids 1384-1478 of Human PCM1.
Applications
Application Notes
IHC-P: 1/200 - 1/500; WB: 1/500 - 1/1000.
Target
Alternative Names
PCM1; pericentriolar material 1; pericentriolar material 1 protein; PTC4; PCM-1; hPCM-1; pericentriolar material 1, PCM1;
Product Background
Antigen Description
Required for centrosome assembly and function. Essential for the correct localization of several centrosomal proteins including CEP250, CETN3, PCNT and NEK2. Required to anchor microtubules to the centrosome. Involved in the biogenesis of cilia.
Pathway
Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Centrosome maturation, organism-specific biosystem; G2/M Transition, organism-specific biosystem; Loss of Nlp from mitotic centrosomes, organism-specific biosystem; Loss of proteins required for interphase microtubule organization??from the centrosome, organism-specific biosystem; Mitotic G2-G2/M phases, organism-specific biosystem;
Citations
Publication ()
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COA
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