Anti-PCF11 monoclonal antibody (DCABH-691)
Mouse anti-Human PCF11 monoclonal antibody for WB, ELISA, sELISA
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Recombinant fragment, corresponding to C terminal amino acids 1465-1555 of Human PCF11 with proprietary tag (NP_056969).
WB: 1 - 5 μg/ml; Sandwich ELISA: 10 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
PCF11; PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae); PCF11, cleavage and polyadenylation factor II subunit, homolog (S. cerevisiae); pre-mRNA cleavage complex 2 protein Pcf11; KIAA0824; PCF11p homolog
Component of pre-mRNA cleavage complex II.
Cleavage of Growing Transcript in the Termination Region, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Processing of Capped Intronless Pre-mRNA, organism-specific biosystem; Processing of Intronless Pre-mRNAs, organism-specific biosystem; RNA Polymerase II Transcription, organism-specific biosystem; RNA Polymerase II Transcription Termination, organism-specific biosystem.
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Zhang, ZQ; Gilmour, DS; et al. Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcript. MOLECULAR CELL 21:65-74(2006).
Grosser, M; Magdolen, V; et al. Gene expression analysis of HUVEC in response to TF-binding. THROMBOSIS RESEARCH 127:259-263(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.