Rabbit Anti-Human PCDHB16 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Fusion protein corresponding to a region derived from internal residues of human protocadherin beta 16

Conjugate

Application Notes

IHC: 1:25-1:100

General Notes

This product (Catalog No. DPABH-03355) is a rabbit-derived IgG polyclonal antibody raised against human PCDHB16. It has been affinity purified by protein A. This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.
DPABH-03355 is suitable for use in IHC (1:25–1:100) application.
DPABH-03355 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

ME1; PCDH3X; PCDHB8a; PCDH-BETA16

Entrez Gene ID

UniProt ID