Anti-PCDH11X (aa 1228-1336) polyclonal antibody

Species Reactivity

Human

Immunogen

PCDH11X (NP_061850, 1228 a.a. ~ 1336 a.a) partial recombinant protein with GST tag. The sequence is AQASALCYSPPLAQAAAISHSSPLPQVIALHRSQAQSSVSLQQGWVQGADGLCSVDQGVQ GSATSQFYTMSERLHPSDDSIKVIPLTTFTPRQQARPSRGDSPIMEEHP

Conjugate

Alternative Names

PCDH11X; protocadherin 11 X-linked; PCDHX; PCDH-X; PCDH11; PPP1R119; protocadherin-11 X-linked; protocadherin-S; protocadherin 11X; protocadherin on the X chromosome; protein phosphatase 1, regulatory subunit 119;

Entrez Gene ID

UniProt ID

Antigen Description

This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 7 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene is located in a major X/Y block of homology and its Y homolog, despite divergence leading to coding region changes, is the most closely related cadherin family member. The protein is thought to play a fundamental role in cell-cell recognition essential for the segmental development and function of the central nervous system. Disruption of this gene may be associated with developmental dyslexia. Alternative splicing results in multiple transcript variants.